The Importance of Medicines


There has been a spate of drug related illnesses and deaths reported from Pakistan in the press this year. In November, at least 17 people died in the eastern city of Lahore after drinking toxic cough syrup. Earlier in January, an adulterated heart medicine dispensed by the Punjab Institute of Cardiology claimed lives of at least 69 heart patients. It seems appropriate to put these happenings in some perspective.  

Cough syrups have been at the center of several cases of mass poisonings around the world in recent years, often involving accidental or intentional use of industrial solvent - diethylene glycol - as a cheap sweetener by the manufacturers. Diethylene glycol is known for causing severe toxicity and death. The effects of such poisoning can be widened because cough syrup is frequently abused by people who use it to get high. It was the most likely scenario in Panama when at least 94 people died from taking cough syrups in 2006.  

A 7-year-old boy died in Manila in February this year after he suffered a seizure believed to have been caused by taking cough medicine. Another five years old fell victim in Colorado, US on February 12 this year after taking the over-the-counter cough medicine to treat flu-like symptoms. Similar incidents are reported from around the world totaling a massive number.  

Besides such clear incidences of toxicity, some seemingly innocuous medicines like iron supplements may account for more than 30% of reported pediatric medicine related fatalities. Antidepressants, cardiovascular medications, and methyl salicylate follow in frequency of pediatric pharmaceutical related deaths.  

Let us take a few steps back and look at the bigger picture. Prescription drugs constitute the major treatment modality of scientific medicine today. Their utility has from the beginning, however, been overrated as manufacturers and promoters of these chemical drugs promised much more than they delivered. Far beyond not working, the drugs are known to cause incalculable side effects. Even when properly prescribed, these drugs have side effects that can be fatal. The situation would seem even worse considering the potential of human error. 

Lazarou has shown that there might be as many as 106,000 deaths annually due to medicinal reactions happening in United States causing around $12 billion in economic losses. These are to be added to an annual figures of 98,000 deaths and &2 billion losses shown by Suh as a result of human errors.  

Besides the incalculable harm caused by the medicines as listed above, the death and suffering caused additionally due to hospital acquired infections, unnecessary procedures including surgeries, negligence and error brought forth by the healer reaches mind boggling dimensions. It would appear that causing harm is a rule rather than exception in the era of modern medicine. 

A look at the broader picture shows that medicine - as conventionally practiced – has failed to meet effectively many of the challenges of modern health care and instead of being part of a solution has become part of the problem. 

Media Contact:  

Allison Grey  

Journal Manager  

Journal of Clinical chemistry and Laboratory Medicne